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PROTECTIVE EFFECT OF POMEGRANATE PEEL EXTRACT ON DIETARY-INDUCED NON-ALCOHOLIC FATTY LIVER DISEASE

Bashir M Ayad
Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver disorders that is generally associated with abnormal liver function test results. Pomegranate has been described as the nature’s power fruit, and shown to have various health benefits. This study aims to explore the role of aqueous pomegranate peel extract (PPE) in attenuating NAFLD induced by high fat diet (HFD). 24 male guinea pigs were allocated into three groups (eight per group). Control (CON) group received normal chow diet. High fat diet (HFD) group, consumed HFD over six weeks to induce NAFLD. HFD-PPE group received HFD for six weeks followed by four weeks administration of PPE tea along with HFD. All animals survived until termination of the experiment, and were ultimately sacrificed at scheduled time (six weeks for the CON and HFD groups and ten weeks for the HFD-PPE group). NAFLD was evaluated histologically and by measuring serum levels of liver enzymes. There was a significant increase in t.


Date Published : 2022-01-11
Date Received : 0000-00-00
23

EXPRESSION OF EXTRACELLULAR MATRIX METALLOPROTEINASE INDUCER (EMMPRIN) AS A BIOMARKER IN ORAL SQUAMOUS CELL CARCINOMA (OSCC)

Ben amer A.M
EMMPRIN is a widely distributed cell surface glycoprotein that belongs to immunoglobulin (Ig) super family. It is inducing the production of extracellular matrix metalloproteinase (MMP) enzymes and play important role in angiogenesis via stimulation of vascular endothelial growth factor (VEGF). The aim of the present work is to evaluate and asses the expression of extracellular matrix metalloproteinase inducer (EMMPRIN) in oral squamous cell carcinomas and to compare the expression of extracellular matrix metalloproteinase inducer (EMMPRIN) in different types of oral squamous cell carcinomas. Thirty diagnosed cases of Oral squamous cell carcinoma (OSCC) were selected and immunohistochemistry was performed for EMMPRIN. All cases showed positive EMMPRIN expression with different intensity. This study concluded that the elevated expression of EMMPRIN levels correlate with tumor proliferation, angiogenesis, metastasis and invasion..


Date Published : 2022-01-11
Date Received : 0000-00-00
10

PREVALENCE OF IRON DEFICIENCY ANEMIA (IDA) AMONGST NURSING STUDENTS OF MISURATA UNIVERSITY, LIBYA

Ayman Mustafa
Iron deficiency anemia (IDA) is the most common type of anemia. Anemia is defined as a clinical condition characterized by a reduction in hemoglobin concentration of blood or the number of red blood cells (RBCs) is poorly below the normal. The present study was conducted to investigate about prevalence of iron deficiency anemia among nursing students and elucidate the correlations between hemoglobin level, gender, physical signs, and clinical symptoms. Sixty-one students aged 18-30 years were selected randomly, during the period from April up to December 2018. Hemoglobin (Hb) level was measured for each respondent. Pearson correlation was used to find a correlation between Hb and other parameters. where P<0.05 was considered statistically significant. The results showed that, there was 16% found to be suffering from anemia, when 28% of females had diagnosed low Hb levels with anemia. A significant (P˂0.05) correlation between Hb level, sex, pale-colored inside lower eyelids, gen.


Date Published : 2022-01-11
Date Received : 0000-00-00
3

PREVALENCE OF VITAMIN D INSUFFICIENCY AND ITS ASSOCIATED RISK FACTORS AMONG PREGNANT WOMEN IN SELECTED CLINICS IN MISURATA, LIBYA

Hawa Omar Eltaweel & et.al
This study was performed to investigate the prevalence of Vitamin D insufficiency and its associated risk factors among pregnant women in selected clinics in Misurata, Libya for the month of March 2018. A total of 90 pregnant women were included in this study. a self-made questionnaire was designed to gather data. The data gathered were classified, tabulated and analyzed using descriptive statistics. Fifty five percent of the respondents had insufficient vitamin D (serum concentration 25 (OH) D level ≤ 30 ng/ml ), Most of the respondents are aged 15-25 years old and are in college level, with fair skin and sometimes exposed to sunlight in the mid-day with less than one hour, sometimes use of sunscreen cream. In terms of dietary information, most of the respondents had regular intake of milk, omega 3 fish oil, Vitamin D and calcium supplements. Despite the increasing awareness of the importance of vitamin D in the recent period, and although pregnant women in Misurata hospitals.


Date Published : 2022-01-11
Date Received : 0000-00-00
1

MUCOSAL BRUCELLA INFECTION IN HUMAN: A CASE REPORT DURING COVID-19 PANDEMIC

Eltaher Elshagmani
Brucellosis in human is an uncommon disease in Libya and usually diagnosed by serological assays. The clinical symptoms of this disease in many times are none specific and vague. This report describes a case of clinical human brucellosis in Libya. The patient was a sixteen years old girl, lives in a rural area. She was suffering from intermittent fever for several days associated with chills, mild cough, and headache. The patient had history of occasional drink of goat’s raw milk during the previous two months. She had no history of travel abroad and direct animal contacts. Comprehensive physical examination revealed the patient was generally unwell, pallor and, had tenderness and mild hepatosplenomegaly. Laboratory investigations revealed that the patient had pancytopenia (low number of blood cells count) and a marked increase in C-reactive protein (CRP), Procalcitonin (PCT), Lactate dehydrogenase (LDH), Aspartate transaminase (AST). Viral screen tests were non-reactive for H.


Date Published : 2022-01-11
Date Received : 0000-00-00
8

ORAL SQUAMOUS CELL CARCINOMAS IN PATIENT WITH GRAFT VERSUS-HOST DISEASE FOLLOWING ALLOGENIC BONE MARROW TRANSPLANTATION. A CASE REPORT DURING MUTANT COVID-19 PANDEMIC

Khaled S. Ben Salah
Aplastic anaemia is a severe haematological disorder characterized by an inadequate number of hematopoietic stem cells, resulting in pancytopenia, formed by a hypocellular bone marrow. Disorders of this nature are widely treated with haematopoietic stem cell transplantation (HSCT). A potential chronic complication following (HSCT) is the growth of secondary malignancies. Notably, patients suffering from chronic graft versus host disease (cGvHD) secondary to HSCT have been shown to be more susceptible to oral squamous cell carcinoma (OSCC). Here, we present a rare case of a 30-year-oldLibyan woman treated with HSCT for aplastic anaemia, with subsequent complications of cGvHD and OSCC after few months of HSCT. These carcinomatous lesions were detected in the buccal gingiva and retromolar pad area at age of 31. The present case report emphasizes on the connection between oral cGvHD and OSCC, and the potential appearance of OSCC after HSCT at any time of patient life. Thus, closer fol.


Date Published : 2022-01-13
Date Received : 0000-00-00
9

REDUCING THE RISK OF URETHROCUTANEOUS FISTULA WITH MODIFIED SNODGRASS HYPOSPADIAS REPAIR: A RETROSPECTIVE STUDY IN MISURATA


The Snodgrass surgical procedure is one of the methods for hypospadias repair. Currently it is the most commonly used hypospadias repair technique, especially for distal hypospadias. It has resulted in sig-nificant improvement in the outcome of hypospadias repair. Multiple modifications to the original procedure are introduced, which may further limit and reduce the risk of complications. In this paper, we review our experience with the modified technique with respect to postoperative complications and outcome, with emphasis on fistula formation. We reviewed the results of 61 cases treated by Snod-grass urethroplasty by the same surgeon, between August 2017and May 2019 at Alnokhba hospital in Misurata-Libya. We divided the patients into three groups, we used in each group a different surgical method. The three methods differed in the type of flap used. In group A (20 boys), the neourethra was covered by a preputual flap. In group B (23 boys), the neo.


Date Published : 2022-01-13
Date Received : 0000-00-00
12

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